Imaging of dialysis-related amyloid (AB-amyloid) deposits with 131I-β2-microglobulin
نویسندگان
چکیده
منابع مشابه
Intermolecular Alignment in β2-Microglobulin Amyloid Fibrils
The deposition of amyloid-like fibrils, composed primarily of the 99-residue protein β2-microglobulin (β2m), is one of the characteristic symptoms of dialysis-related amyloidosis. Fibrils formed in vitro at low pH and low salt concentration share many properties with the disease related fibrils and have been extensively studied by a number of biochemical and biophysical methods. These fibrils c...
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Several protein misfolding diseases are associated with the conversion of native proteins into ordered protein aggregates known as amyloid. Studies of amyloid assemblies have indicated that non-native proteins are responsible for initiating aggregation in vitro and in vivo. Despite the importance of these species for understanding amyloid disease, the structural and dynamic features of amyloido...
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K. L. Hultman, J. L. Lack, T. M. Wengenack, G. L. Curran, G. M. Preboske, R. Muthu, M. Garwood, C. R. Jack Jr, and J. F. Poduslo Molecular Neurobiology, Mayo Clinic College of Medicine, Rochester, MN, United States, Radiology, Mayo Clinic College of Medicine, Rochester, MN, United States, Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis, MN, United States
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ژورنال
عنوان ژورنال: Kidney International
سال: 1990
ISSN: 0085-2538
DOI: 10.1038/ki.1990.329